Tetanus

Tetanus, or lockjaw, disease of the nervous system caused by toxins produced by the bacterium Clostridium tetani. The bacteria enter the body through breaks in the skin. The first symptom is often painful contraction of jaw and neck muscles; trunk muscles, including those of respiration, and muscles close to the site of injury are also frequently involved. Untreated, many cases are fatal, but artificial respiration, antiserum, and penicillin have improved the outlook. Regular vaccination and adequate wound cleansing are important in prevention.