Gaucher's disease

Gaucher's disease, rare, sometimes hereditary, disorder of lipid metabolism resulting in an abnormal accumulation of fats and fatlike substances (lipids) in the liver and spleen, greatly enlarging those organs, as well as jaundice, skeletal lesions, and anemia. The disease is the result of the body's inability to produce enzymes to break down fats. It is incurable, although surgical removal of the spleen can relieve some of the symptoms.